Merck’s Molnupiravir (EIDD-281) Effective Against SARS-COV-2 | drbeen
Author declares no conflict of interest.
Get free trial
with access to all our lectures
DrBeen Logo

no credit card required

My Notes

Become a member to create study notes.
Sign up for free trial
Merck’s Molnupiravir (EIDD-281) Effective Against SARS-COV-2 Duration: 1751
Microbiology / Virology
Flashcards Video notes

Learning Objectives

Merck has a new drug molecule for SARS-COV-2. It is named Molnupiravir or EIDD-2801. We will discuss the following topics about this drug.

 

  1. Need for this anti-viral drug to be used with Remdesivir.
  2. History of the EIDD-2801.
  3. Trial for phase II and phase III.
  4. Route of administration.
  5. Drug properties.
  6. Mechanism of action.
  7. Results in mouse studies.
  8. Therapeutic index.

Instructor

Dr. Mobeen Syed

Dr. Mobeen Syed

Mobeen Syed M.D, MS Graduated from King Edward Medical University. Entrepreneur, Medical Educator, CEO and founder of Drbeen corp.


Videos in this series

COVID-19 (by SARS-COV-2) Debunking Myths and Rumors COVID-19 (by SARS-COV-2) Debunking Myths and Rumors
SARS-COV-2 (Novel Coronavirus) - An Introduction SARS-COV-2 (Novel Coronavirus) - An Introduction
All About SARS-COV-2 and COVID-19 (March 31st Update) All About SARS-COV-2 and COVID-19 (March 31st Update)
Similarities and Differences between COVID-19 (by SARS-COV-2) and the Seasonal Flu Similarities and Differences between COVID-19 (by SARS-COV-2) and the Seasonal Flu
SARS-COV-2 Case Fatality Rate (Death Rates) SARS-COV-2 Case Fatality Rate (Death Rates)
COVID-19 (by SARS-COV-2) Healthcare Burden Assessment COVID-19 (by SARS-COV-2) Healthcare Burden Assessment
Can Hydroxychloroquine Work as An Antiviral? Can Hydroxychloroquine Work as An Antiviral?
Management Principles Of COVID-19 (March 20th Update) Management Principles Of COVID-19 (March 20th Update)
Vitamin C - Can it Help Fight COVID-19? Vitamin C - Can it Help Fight COVID-19?
Vitamin D - Can It Help Fight COVID-19? Vitamin D - Can It Help Fight COVID-19?
Convalescent Plasma For COVID-19 Patients Convalescent Plasma For COVID-19 Patients
SARS-COV-2 Testing SARS-COV-2 Testing
Vaccination Strategies for SARS-COV-2 (COVID-19) Vaccination Strategies for SARS-COV-2 (COVID-19)
Does SARS-COV-2 Attack Blood/Hemoglobin? Does SARS-COV-2 Attack Blood/Hemoglobin?
Asymptomatic Patients of COVID-19 Asymptomatic Patients of COVID-19
Could BCG Vaccine Help Fight COVID-19? Could BCG Vaccine Help Fight COVID-19?
Herd Immunity and Second Wave Herd Immunity and Second Wave
Quercetin as Zinc Ionophore & Outpatient Management Quercetin as Zinc Ionophore & Outpatient Management
Will COVID-19 Slowdown? Will COVID-19 Slowdown?
COVID-19 and Diabetes COVID-19 and Diabetes
Is Reinfection From SARS-COV-2 Possible? Is Reinfection From SARS-COV-2 Possible?
Asymptomatic COVID-19 Patients Asymptomatic COVID-19 Patients
Remdesivir: Mechanism of Action Remdesivir: Mechanism of Action
Natural Killer Cells Natural Killer Cells
New Study Hydroxychloroquine New Study Hydroxychloroquine
Heart Patients And COVID-19 Heart Patients And COVID-19
Lifting the Lockdown Lifting the Lockdown
BCG Vaccine BCG Vaccine
Hypercoagulability Role of the ACE2 Enzyme - Part 1 Hypercoagulability Role of the ACE2 Enzyme - Part 1
COVID-19 Insights: Hypertension and COVID-19 COVID-19 Insights: Hypertension and COVID-19
Hypercoagulability - Part 2 (Coagulation cascade) Hypercoagulability - Part 2 (Coagulation cascade)
First COVID-19 Case in The USA First COVID-19 Case in The USA
COVID-19 Insights: Mutations in SARS-COV-2 COVID-19 Insights: Mutations in SARS-COV-2
Asthma and COVID-19 Asthma and COVID-19
COVID-19 Insights: Monoclonal Antibodies COVID-19 Insights: Monoclonal Antibodies
COVID-19 Insights: Cancer Patients and COVID-19 COVID-19 Insights: Cancer Patients and COVID-19
LATEST on Vaccines for COVID-19 LATEST on Vaccines for COVID-19
COVID-19 Severity and Blood Groups COVID-19 Severity and Blood Groups
COVID-19 and Sickle Cell, Thalassemia, and Hemophilia (Full Session) COVID-19 and Sickle Cell, Thalassemia, and Hemophilia (Full Session)
NAC N-Acetylcysteine NAC N-Acetylcysteine
G6PD Enzyme Deficiency and COVID-19 G6PD Enzyme Deficiency and COVID-19
Global View of COVID-19 - (HCQ and Zinc New Studies) Global View of COVID-19 - (HCQ and Zinc New Studies)
Camostat Mesylate Camostat Mesylate
Oxford and Moderna Vaccines News Part 1 Oxford and Moderna Vaccines News Part 1
Oxford and Moderna Vaccines News Part 2 Oxford and Moderna Vaccines News Part 2
COVID-19 Leronlimab COVID-19 Leronlimab
CoQ10 (Co-Enzyme Q) CoQ10 (Co-Enzyme Q)
COVID-19 Cases and Test Accuracy COVID-19 Cases and Test Accuracy
MATH+ Protocol For COVID-19 (Part 1) MATH+ Protocol For COVID-19 (Part 1)
Tocilizumab An IL6 Receptor Blocker Tocilizumab An IL6 Receptor Blocker
Is SARS-COV-2 Becoming Weak? Is SARS-COV-2 Becoming Weak?
MATH+ Protocol - ICU Management (Part 3) MATH+ Protocol - ICU Management (Part 3)
Magnesium Magnesium
Melatonin Melatonin
COVID-19 and Aspirin COVID-19 and Aspirin
COVID-19 and Epoprostenol (Hypercoagulation Management) COVID-19 and Epoprostenol (Hypercoagulation Management)
MATH+ Protocol - In Hospital Management (Part 2) MATH+ Protocol - In Hospital Management (Part 2)
Vitamin K Deficiency and COVID-19 Vitamin K Deficiency and COVID-19
Vitamin K (Math+ Protocol) Vitamin K (Math+ Protocol)
Thiamine for COVID-19 (HAT Study and MATH+ Protocol) Thiamine for COVID-19 (HAT Study and MATH+ Protocol)
Iodine and Its Medical Uses Iodine and Its Medical Uses
Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy)
Dexamethasone Dexamethasone
MATH+ Protocol - Latest Updates MATH+ Protocol - Latest Updates
Low Dose Radiation for COVID-19 Low Dose Radiation for COVID-19
Favipiravir Favipiravir
COVID-19 Vaccines Update (Aug 3rd 2020) COVID-19 Vaccines Update (Aug 3rd 2020)
COVID-19 and Selenium (Part of MATH+ Protocol) COVID-19 and Selenium (Part of MATH+ Protocol)
COVID-19 and Ivermectin, Remdesivir, Leronlimab COVID-19 and Ivermectin, Remdesivir, Leronlimab
A Potential Rare Case of Meningitis With COVID-19 A Potential Rare Case of Meningitis With COVID-19
A Potentially Rare Case of Meningitis with COVID-19 (Labs) A Potentially Rare Case of Meningitis with COVID-19 (Labs)
Norepinephrine Norepinephrine
Famotidine (H2 Receptor Antagonist) Famotidine (H2 Receptor Antagonist)
Hydroxychloroquine and Azithromycin Studies Hydroxychloroquine and Azithromycin Studies
Inhaled Corticosteroids (Budesonide) Inhaled Corticosteroids (Budesonide)
Macrolide - Azithromycin Macrolide - Azithromycin
Children Have Better Immune Systems Children Have Better Immune Systems
Boosting The Innate Arm of Your Immune System Boosting The Innate Arm of Your Immune System
Ivermectin, Abbott, Sniffer Dogs and ICAM Protocol Ivermectin, Abbott, Sniffer Dogs and ICAM Protocol
Must Watch- COVID-19 Management With Dr. Paul Marik - Author Of MATH+ Protocol Must Watch- COVID-19 Management With Dr. Paul Marik - Author Of MATH+ Protocol
Dosage For Vitamin D, K2, and Calcium Dosage For Vitamin D, K2, and Calcium
Icelandic Study - Antibody Immunity Lasts Longer Icelandic Study - Antibody Immunity Lasts Longer
Bromhexine Study, SARS-COV-2 Antibody Cocktail Bromhexine Study, SARS-COV-2 Antibody Cocktail
News, Mini Proteins, UVC 222nm, CDC News, Mini Proteins, UVC 222nm, CDC
Bromhexine Protocol By Dr. Harrison Bromhexine Protocol By Dr. Harrison
Is a Positive PCR Test Really Positive Is a Positive PCR Test Really Positive
Vaccines Update, NEJM Weighs In Vaccines Update, NEJM Weighs In
A Case of Reinfection A Case of Reinfection
Brain Fog and Other Symptoms In Long Haulers Brain Fog and Other Symptoms In Long Haulers
Seasonal Specific Antibodies and Severity of COVID-19 Seasonal Specific Antibodies and Severity of COVID-19
Dr. Zelenko Discusses COVID-19 Outpatient Management Dr. Zelenko Discusses COVID-19 Outpatient Management
Latest Study Early Management with HCQ - Dr. Zelenko Latest Study Early Management with HCQ - Dr. Zelenko
Ivermectin Works For COVID-19 Ivermectin Works For COVID-19
High Dose Thiamine And Cytokine Storm High Dose Thiamine And Cytokine Storm
FDA Approves Remdesivir for COVID-19 FDA Approves Remdesivir for COVID-19
Hydroxychloroquine Studies Are Still Confusing Hydroxychloroquine Studies Are Still Confusing
Ranitidine Bismuth Citrate (RBC) For COVID-19 Ranitidine Bismuth Citrate (RBC) For COVID-19
Vaccine Update- BioNTech and Pfizer’s Vaccine Vaccine Update- BioNTech and Pfizer’s Vaccine
Ivermectin Reduces Mortality Ivermectin Reduces Mortality
Mouth Washes That Inactivate Coronaviruses Mouth Washes That Inactivate Coronaviruses
Two Studies About Vitamin C and D Two Studies About Vitamin C and D
Declining Prevalence of Antibody Positivity to SARS-CoV-2 Declining Prevalence of Antibody Positivity to SARS-CoV-2
How SARS-COV-2 Disrupts Our Defense How SARS-COV-2 Disrupts Our Defense
Preliminary Predictive Criteria for COVID-19 Cytokine Storm Preliminary Predictive Criteria for COVID-19 Cytokine Storm
Introduction To P Values and Power Introduction To P Values and Power
Cloth Masks Do Not Cause Hypoxia Cloth Masks Do Not Cause Hypoxia
Antibody Immunity Lasts And Matures At 6 Months Antibody Immunity Lasts And Matures At 6 Months
AstraZeneca Vaccine is 62% and 90% Effective AstraZeneca Vaccine is 62% and 90% Effective
Dr. Paul Marik Discusses His I-MASK+ Protocol Dr. Paul Marik Discusses His I-MASK+ Protocol
Honey and Nigella Sativa For COVID-19 Honey and Nigella Sativa For COVID-19
Moderna VS Pfizer: Which is better Moderna VS Pfizer: Which is better
Minks and Masks (WHO and CDC) Minks and Masks (WHO and CDC)
Regeneron Antibody Cocktail Regeneron Antibody Cocktail
COVID-19-Pregnant Women and Young Babies COVID-19-Pregnant Women and Young Babies
New Strain from the UK- Should We Worry? New Strain from the UK- Should We Worry?
Allergic Reactions to Pfizer-BionTech Vaccine in UK Allergic Reactions to Pfizer-BionTech Vaccine in UK
Ivermectin Alone More Effective Than Ivermectin and Doxycycline Ivermectin Alone More Effective Than Ivermectin and Doxycycline
Latest Update About Vaccines (Dec 28th, 2020) Latest Update About Vaccines (Dec 28th, 2020)
COVID Long Haulers - Discussion With Dr. Bruce Patterson COVID Long Haulers - Discussion With Dr. Bruce Patterson
AstraZeneca Vaccine And Our Nucleus AstraZeneca Vaccine And Our Nucleus
Will the vaccine continue to make spike proteins Will the vaccine continue to make spike proteins
Severe Reactions By Pfizer-BioNTech Vaccine Severe Reactions By Pfizer-BioNTech Vaccine
SARS-COV-2 - New Brazilian Strain P.1 Manaus SARS-COV-2 - New Brazilian Strain P.1 Manaus
Antibody-dependent Enhancement of Coronavirus Antibody-dependent Enhancement of Coronavirus
J&J Vaccine - Interim Results For Phase 1 and 2 J&J Vaccine - Interim Results For Phase 1 and 2
South African SARS-COV-2 Variant South African SARS-COV-2 Variant
What Antibody Levels Are Necessary For COVID-19 Protection What Antibody Levels Are Necessary For COVID-19 Protection
Moderna vs. Pfizer-BioNTech Vaccines - An Initial Comparison Moderna vs. Pfizer-BioNTech Vaccines - An Initial Comparison
Vitamin D, Dust and Covid-19 Vitamin D, Dust and Covid-19
Recommendation For Immunization Practices From CDC Recommendation For Immunization Practices From CDC
Ivermectin Mechanism of Action Ivermectin Mechanism of Action
Covaxin, A Vaccine from India Covaxin, A Vaccine from India
Sinopharm's COVID-19 Vaccine Sinopharm's COVID-19 Vaccine
Vaccination Results From Israel Vaccination Results From Israel
J&J Vaccine - Pandemic Will Be Over Soon J&J Vaccine - Pandemic Will Be Over Soon
Sputnik Vaccine is 91.6% Effective Sputnik Vaccine is 91.6% Effective
Fluvoxamine - Important for Long Haulers Fluvoxamine - Important for Long Haulers
Covid-19- Testicular Damage and Infertility Covid-19- Testicular Damage and Infertility
Interferon Beta - A New Study Interferon Beta - A New Study
AstraZeneca Vaccine Efficacy Update AstraZeneca Vaccine Efficacy Update
Vitamin D Cuts COVID Deaths by 60% Vitamin D Cuts COVID Deaths by 60%
Colchicine Reduces COVID Intensity and Deaths Colchicine Reduces COVID Intensity and Deaths
COVID Long Hauler COVID Long Hauler
COVID Long Haulers - Mast Cell Activation Syndrome (MCAS) Part - 1 COVID Long Haulers - Mast Cell Activation Syndrome (MCAS) Part - 1
COVID Long Haulers - Mast Cell Activation Syndrome (MCAS) - Part 2 (Symptoms and Management) COVID Long Haulers - Mast Cell Activation Syndrome (MCAS) - Part 2 (Symptoms and Management)
Will Ivermectin Block a Vaccine? Will Ivermectin Block a Vaccine?
How is AstraZeneca Vaccine Made How is AstraZeneca Vaccine Made
Ivermectin Still Effective Against The Variants Ivermectin Still Effective Against The Variants
Johnson and Johnson Vaccine Efficacy (Approval Data) Johnson and Johnson Vaccine Efficacy (Approval Data)
Ivermectin May Help Against Blood Coagulation in COVID Ivermectin May Help Against Blood Coagulation in COVID
More Deaths by The UK Variant More Deaths by The UK Variant
Novavax Phase III and Phase II B Trial Results Novavax Phase III and Phase II B Trial Results
Nasal Spray for Virus/SARS-COV-2 Reduction Nasal Spray for Virus/SARS-COV-2 Reduction
Merck’s Molnupiravir (EIDD-281) Effective Against SARS-COV-2 Merck’s Molnupiravir (EIDD-281) Effective Against SARS-COV-2
  • currently watching
Deaths, Anaphylaxis, And Other Vaccine Adverse Effects (March 16th 2021 - USA) Deaths, Anaphylaxis, And Other Vaccine Adverse Effects (March 16th 2021 - USA)
Covid 19 Symptoms in Kids Covid 19 Symptoms in Kids
Vaccine-Induced Clotting- Management Vaccine-Induced Clotting- Management
Vaccine After COVID (A Study) Vaccine After COVID (A Study)
Scientists Develop a New Corona Vaccine to Fight All Mutants and Strains of Coronavirus Scientists Develop a New Corona Vaccine to Fight All Mutants and Strains of Coronavirus
Super Vaccine for Coronavirus- More Updates Super Vaccine for Coronavirus- More Updates
Israel Pfizer Vaccine Efficacy At a Large Scale Israel Pfizer Vaccine Efficacy At a Large Scale
Pfizer Vaccine Associated Adverse Effects From Israel Pfizer Vaccine Associated Adverse Effects From Israel
Risk Of Rare Blood Clotting Higher for COVID- 19 than for Vaccines Risk Of Rare Blood Clotting Higher for COVID- 19 than for Vaccines
New Technique To Study COVID Pathology (High Parameter Imaging Mass Cytometry) New Technique To Study COVID Pathology (High Parameter Imaging Mass Cytometry)
Double Mutant Variant in India (B.1.167) Double Mutant Variant in India (B.1.167)
Increased Breakthrough Rates Of South African Variant From Pfizer-BioNTech Vaccine - An Israeli Study Increased Breakthrough Rates Of South African Variant From Pfizer-BioNTech Vaccine - An Israeli Study
Administration of Second Dose Of Moderna Vaccine After An Immediate Hypersensitivity Reaction to The First Dose Administration of Second Dose Of Moderna Vaccine After An Immediate Hypersensitivity Reaction to The First Dose
Mixing Vaccine Types - UK Study Mixing Vaccine Types - UK Study
COVID-19 Primarily A Vascular Disease COVID-19 Primarily A Vascular Disease
COVID Long Haul Management Protocol COVID Long Haul Management Protocol
IVIg A High Level Overview IVIg A High Level Overview
Non-Neutralizing Antibodies From mRNA Vaccines Non-Neutralizing Antibodies From mRNA Vaccines
Pfizer Vaccine For Kids 12 Years and Above Granted EUA By FDA Pfizer Vaccine For Kids 12 Years and Above Granted EUA By FDA
Low Histamine Diets Low Histamine Diets
MHC I and MHC II Loading MHC I and MHC II Loading
Vaccines and Variants (Neutralizing Antibodies vs., Binding Antibodies) Vaccines and Variants (Neutralizing Antibodies vs., Binding Antibodies)
New Ivermectin Study By Prof. Eli Schwartz  New Ivermectin Study By Prof. Eli Schwartz 
SARS-COV-2 Natural Infections Protects Against Reinfection With 95% Efficacy SARS-COV-2 Natural Infections Protects Against Reinfection With 95% Efficacy
Lifelong Protection After COVID Infection (Study) Lifelong Protection After COVID Infection (Study)
Soluble Spike Proteins by Vaccines? Soluble Spike Proteins by Vaccines?
Do Vaccinated Individuals Shed Spike Proteins? Do Vaccinated Individuals Shed Spike Proteins?
Innate Immune System Reprogramming By Pfizer-BioNTech Vaccine Against SARS-COV-2? Innate Immune System Reprogramming By Pfizer-BioNTech Vaccine Against SARS-COV-2?
Ivermectin and COVID Anosmia A Review of Studies Ivermectin and COVID Anosmia A Review of Studies
Early COVID Has Signs For Severe and Long Haul Outcomes Early COVID Has Signs For Severe and Long Haul Outcomes
Are Vaccines Causing Variants Are Vaccines Causing Variants
Vaccine Adverse Events in the US VAERS System Vaccine Adverse Events in the US VAERS System
Vaccines are Highly Effective Against Hospitalization from the Delta Variant Vaccines are Highly Effective Against Hospitalization from the Delta Variant
Breakthrough After Vaccines and After The Natural Infection Breakthrough After Vaccines and After The Natural Infection
Spike Protein Cytotoxicity Spike Protein Cytotoxicity
A Study - Spike Proteins in Plasma of Vaccinated (Nothing After The Second Dose) A Study - Spike Proteins in Plasma of Vaccinated (Nothing After The Second Dose)
SARS-COV-2 Spikes in Ovaries from Pfizer-BioNTech Vaccine SARS-COV-2 Spikes in Ovaries from Pfizer-BioNTech Vaccine
Non-Classical Monocytes Causing Long Haul Non-Classical Monocytes Causing Long Haul
Post-COVID Long Haul Syndrome (PCLHS) Management Post-COVID Long Haul Syndrome (PCLHS) Management
Irregular Periods And Vaccines Irregular Periods And Vaccines
Absolute Risk Reduction vs Relative Risk Reduction Absolute Risk Reduction vs Relative Risk Reduction
Vaccine Caused Clotting - Study Finds The Mechanism Vaccine Caused Clotting - Study Finds The Mechanism
COVID-19 Causes Long-Term Blood Cell Changes COVID-19 Causes Long-Term Blood Cell Changes
Is Intravenous Vaccine Causing Clotting Is Intravenous Vaccine Causing Clotting
Delta Variant And Deaths In 50+ Delta Variant And Deaths In 50+
Delta Variant UK Analysis Delta Variant UK Analysis
99.995% of Children Survive COVID-19 Uk Data Shows 99.995% of Children Survive COVID-19 Uk Data Shows
Epstein Barr Virus (EBV) - Long COVID Epstein Barr Virus (EBV) - Long COVID
Maraviroc Mechanism of Action (MOA) Maraviroc Mechanism of Action (MOA)
Epstein Barr Virus (EBV) Serology Epstein Barr Virus (EBV) Serology
How Ivermectin Helps with Epstein Barr Virus (EBV) How Ivermectin Helps with Epstein Barr Virus (EBV)
Epstein Barr Virus Reactivation in COVID Epstein Barr Virus Reactivation in COVID
Epstein Barr Virus Prevalence in Long COVID Epstein Barr Virus Prevalence in Long COVID
Delta, Viral Burden Vaccine Effectiveness Against New SARS-CoV-2 Infections In The UK Delta, Viral Burden Vaccine Effectiveness Against New SARS-CoV-2 Infections In The UK
Researchers Show How SARS-COV-2 Spike Protein Causes Acute Lung Injury in Mice Researchers Show How SARS-COV-2 Spike Protein Causes Acute Lung Injury in Mice
All About the Mu Variant All About the Mu Variant