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1. Origin of MAPK pathway nomenclature.
2. Mechanisms involving:
- Platelet-derived growth factors
- Transforming growth factors
- Epidermal growth factors
- Nerve growth factors
-Insulin, GPCRs, cytokines
- Osmotic stress, microtubule disorganization
3. Clinical significance:
- Cancer and uncontrolled growth
- MAPK/ERK modulators as therapies
4. Developmental abnormalities:
- Noonan syndrome
- Rasopathies
5. Cellular stress response:
- Autocrine and paracrine actions of growth factors
6. Key proteins:
- GRB2
- SOS
7. MAPK pathway roles in:
- Proliferation
- Differentiation
- Development
- Inflammation
- Apoptosis
- Stress response
- Survival response
8. Natural modulators of the MAPK pathway.
Instructor
Dr. Mobeen Syed
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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