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In this fascinating in-vitro and ex-vivo study the researchers from Harvard Boston and Cairo found the mechanism of impaired immune system during the cold temperatures. Researchers found that the extracellular vesicles produced as a result of toll-like receptor 3 (TLR3) are functionally impaired and reduced in numbers when the temperature drops in the anterior nasal mucosa even by 9 degrees Fahrenheit. Let's review this fascinating study.
Cold exposure impairs extracellular vesicle swarm–mediated nasal antiviral immunity - Journal of Allergy and Clinical Immunology https://www.jacionline.org/article/S0091-6749(22)01423-3/fulltext#%20
Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity https://www.jacionline.org/action/showPdf?pii=S0091-6749%2822%2901423-3
MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19 - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910799/#:~:text=In%20fact%2C%20miRNAs%20have%20been,or%20by%20enhancing%20the%20expression
Why colds and flu viruses are more common in winter | CNN https://www.cnn.com/2022/12/06/health/why-winter-colds-flu-wellness/index.html
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2 Comments
empower@*.com
May 12 2023, 2:55 am
Wonderful new video. Great illustrations too 😎. I knew my poor nose needed to stay warm!
anne.fulbright@*.com
Apr 03 2023, 12:26 pm
My nose gets warmer when I sip tea in the morning. Although my habit of opening bedroom windows during cool nights may have to be curtailed. Cool study, thank you!