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Dr. Syed presents type II hypersensitivity reactions. A quick difference between the four types of allergic reactions is discussed.
Characteristics of the type II hypersensitivity reactions. The role of antigen. Attachment of the antigen on the surface of a tissue.
Antigen binding configuration and its significance.
Penicillin reaction causing type II hypersensitivity reaction.
Mechanisms of the tissue damage during the type II hypersensitivity reactions.
Cytotoxic mechanisms, inflammatory mechanisms, and cellular mechanisms of damage are discussed.
Pernicious Anemia
Grave's diseases
Diabetes Mellitus
Neutrophils and their activation causing small vessel vasculitis.
1. The difference between four types of hypersensitivity reacions.
2. The immunopathological mechanism of Type II hypersensitivity reactions.
3. Subtypes of Type II hypersensitivity reaction and their mechanism of injury .
4. Different diseases associated with different subtypes.
5. Pathophysiology of myasthenia gravis and Graves' disease.
6. Pathophysiology of good pasture's syndrome and vasculitis.
7. Mechanism of injury of autoimmune hemolytic anemia and transfusion reactions.
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