In this article, researchers from Switzerland demonstrate the breakdown of self-tolerance against the myelin sheath temporally associated with the mRNA COVID-19 vaccine. In both patients, the self reactive CD4+ T cells against the spike protein were found. These helper T cells attacked the peptides in myeline sheath e.g. MBP, PLP, MOG, etc. Let's review the research, their method, and the conclusion.
Multiple Sclerosis Journal - Volume 28, Number 3_suppl, Oct 01, 2022
https://journals.sagepub.com/toc/msja/28/3_suppl
ECTRIMS 2022 – ePoster
https://journals.sagepub.com/doi/epub/10.1177/13524585221123682
Epstein–Barr virus and multiple sclerosis | Nature Reviews Microbiology
https://www.nature.com/articles/s41579-022-00770-5#:~:text=Epstein%E2%80%93Barr%20virus%20(EBV)%20may%20drive%20inflammatory%20events%20in,sclerosis%20lesion%20in%20the%20CNS.
Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more
https://journals.sagepub.com/doi/pdf/10.1177/1756285611433772
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MD., MSc., MSc., BSc
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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bemdavida@*.com
Sep 08 2023, 8:33 pm
Pls discuss how the self tolerance is disturbed leading to MS!