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Two Cases of Multiple Sclerosis After mRNA Vaccine

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Sep 08 2023, 8:33 pm

Pls discuss how the self tolerance is disturbed leading to MS!

In this article, researchers from Switzerland demonstrate the breakdown of self-tolerance against the myelin sheath temporally associated with the mRNA COVID-19 vaccine. In both patients, the self reactive CD4+ T cells against the spike protein were found. These helper T cells attacked the peptides in myeline sheath e.g. MBP, PLP, MOG, etc. Let's review the research, their method, and the conclusion.

Multiple Sclerosis Journal - Volume 28, Number 3_suppl, Oct 01, 2022

ECTRIMS 2022 – ePoster

Epstein–Barr virus and multiple sclerosis | Nature Reviews Microbiology,sclerosis%20lesion%20in%20the%20CNS.

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more

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