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Streptococcus Pyogenes - Clinical Foundations

Duration: 13:42

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Sep 27 2018, 8:16 pm

Make sure that you grasp the concept of the M proteins and their role in preventing phagocytosis, and then body's response to opsonize them. Mobeen

We are sure that strep/sore throat is a routine presentation in your clinic. In the US only streptococci pyogenes cause millions of yearly visits to healthcare facilities. Streptococci cause disease by direct organ invasion, by their enzymes, and by releasing exotoxins. Understanding streptococci thoroughly and then wielding a great command over the management approach will help you continue to be amazing for your patients. In this two-part series, we will talk about the streptococcal foundations necessary to understand and manage the disease, and then various diseases and their management. Let's start with the first part here. Make sure that you have understood this before the second part about the diseases and their management.

In this lecture we will discuss the following topics:

  • Virulence potential
  • Habitat
    • Throat
    • Skin
  • Tests
    • Erythrogenic/Pyogenic exotoxin
    • Gram +
    • PYR +
    • RAD
    • Catalase -
    • Bacitracin sensitive
  • Antigenic components of the cell wall
    • Hyaluronic acid
    • C carbs
    • M Proteins
    • Exotoxins
  • Enzymes
    • Streptolysin O
    • Streptolysin S
    • Streptokinase
    • Hyaluronidase
    • DNAse
    • C5a Peptidase

These foundations will be used to look at the disease process, disease types, and the disease management in the next lecture.

* Acknowledge the high virulence of Streptococcus pyogenes.

* Appreciate the importance of key structures like the capsule.

* Identify the process of opsonization and its role in immune recognition and clearance of Streptococcus pyogenes.

* Recognize the roles of key enzymes such as Streptolysin O, Streptolysin S, and Streptokinase in tissue destruction and immune evasion.

* Understand the clinical manifestations linked with Streptococcus pyogenes infections, including scarlet fever and toxic shock syndrome.

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.


In addition to the presenter, following authors may have helped with the content writing, review, or approval:

  • Dr. Mobeen Syed

CME, CE, CEU and Other Credit Types:

ACCME Accreditation Statement
The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure Information

In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Dr. Mobeen Syed Author declares no conflict of interest.

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Dr. Mobeen Syed

Dr. Mobeen Syed

MD., MSc., MSc., BSc

Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.


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