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Streptococcus Pyogenes - Clinical Foundations

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mobeen@*.com

Sep 27 2018, 8:16 pm

Make sure that you grasp the concept of the M proteins and their role in preventing phagocytosis, and then body's response to opsonize them. Mobeen

We are sure that strep/sore throat is a routine presentation in your clinic. In the US only streptococci pyogenes cause millions of yearly visits to healthcare facilities. Streptococci cause disease by direct organ invasion, by their enzymes, and by releasing exotoxins. Understanding streptococci thoroughly and then wielding a great command over the management approach will help you continue to be amazing for your patients. In this two-part series, we will talk about the streptococcal foundations necessary to understand and manage the disease, and then various diseases and their management. Let's start with the first part here. Make sure that you have understood this before the second part about the diseases and their management.

In this lecture we will discuss the following topics:

  • Virulence potential
  • Habitat
    • Throat
    • Skin
  • Tests
    • Erythrogenic/Pyogenic exotoxin
    • Gram +
    • PYR +
    • RAD
    • Catalase -
    • Bacitracin sensitive
  • Antigenic components of the cell wall
    • Hyaluronic acid
    • C carbs
    • M Proteins
    • Exotoxins
  • Enzymes
    • Streptolysin O
    • Streptolysin S
    • Streptokinase
    • Hyaluronidase
    • DNAse
    • C5a Peptidase


These foundations will be used to look at the disease process, disease types, and the disease management in the next lecture.

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