How do staphylococci cause toxic shock syndrome? 
Superantigens are the answer. 
In this important video session, Dr. Syed discusses superantigens in the context of staphylococci.

Following topics are discussed:

• What are superantigens?
• What important pathogens release superantigens?
• What superantigens are released?
• Normal controlled immune response to an antigen.
• How does a superantigen cause massive abnormal activation of the immune system?
• Symptoms of the toxic shock syndrome as a result of superantigen activity.
• Labs