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Neuropathic Pain and The Role of Sensory Ganglion (Pain Part 3)

Duration: 51:28

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2 Comments

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najibghazni@*.com

Jan 07 2024, 7:20 pm

thanks mr been very useful information

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mobeen@*.com

Jan 06 2024, 10:38 pm

You are welcome.

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nas@*.com

Jan 05 2024, 7:01 pm

thank you very interesting

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mobeen@*.com

Jan 06 2024, 10:45 pm

Welcome.

Some individuals suffering from neuropathic pain experience pins and needles, hot or cold, buzzing, and burning sensations in their body or parts of the body. There are many possibilities for these symptoms, however, in today's talk, we will discuss the role of sensory ganglion pathology in such neuropathic pains.

We will discuss the following:
1. Definition of Neuropathic Pain.
2. Sensory Ganglion Structure.
3. Sensory Ganglion Blood Supply Difference from the Blood Brain Barrier.
4. The Satellite Glial Cells in Sensory Ganglions.
5. Centrifugal Signal Transmission from the Sensory Ganglions and Tissue Inflammation.
6. Centripetal Signal Transmission from the Sensory Ganglions and Paraesthesia.

 


Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports | Current Pain and Headache Reports
https://link.springer.com/article/10.1007/s11916-022-01065-3

Functional Anatomy of the Sensory Nervous System: Updates From the Neuroscience Bench - LaTasha K. Crawford, Michael J. Caterina, 2020
https://journals.sagepub.com/doi/10.1177/0192623319869011

Tissue-resident M2 macrophages directly contact primary sensory neurons in the sensory ganglia after nerve injury - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513227/

SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model | Science Signaling
https://www.science.org/doi/10.1126/scisignal.ade4984

Neuropathic symptoms with SARS-CoV-2 vaccination - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128783/

How Is Peripheral Injury Signaled to Satellite Glial Cells in Sensory Ganglia? - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8833977/

Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling | eLife
https://elifesciences.org/articles/78515

Neuropathic Pain: From Mechanisms to Treatment | Physiological Reviews
https://journals.physiology.org/doi/full/10.1152/physrev.00045.2019

ILF3 - Wikipedia
https://en.wikipedia.org/wiki/ILF3

Calcitonin gene-related peptide - Wikipedia
https://en.wikipedia.org/wiki/Calcitonin_gene-related_peptide

What are satellite glial cells? — Brain Stuff
https://brainstuff.org/blog/what-are-satellite-glial-cells

Capillaries - Physiopedia
https://www.physio-pedia.com/Capillaries

Mechanics of endothelial cell architecture and vascular permeability - PubMed
https://pubmed.ncbi.nlm.nih.gov/11417757/

Substance P - Wikipedia
https://en.wikipedia.org/wiki/Substance_P

 Understand the clinical features, diagnosis, and potential mechanisms of Complex Regional Pain Syndrome (CRPS).

Grasp the historical development of neuropathic pain research, key concepts, and current scientific understanding.

Differentiate the roles of neurons, nociceptors, and peripheral nerves in pain transmission, with emphasis on their involvement in neuropathic pain pathways.

Distinguish between the anatomical and functional characteristics of spinal and peripheral nerves for accurate pain pathway mapping.

Master the current International Association for the Study of Pain (IASP) definition of neuropathic pain, enabling differentiation from other pain types.

Explore the cellular and molecular changes within sensory ganglia that contribute to chronic pain after peripheral nerve injury.

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Faculty

In addition to the presenter, following authors may have helped with the content writing, review, or approval:

  • Dr. Mobeen Syed

CME, CE, CEU and Other Credit Types:

ACCME Accreditation Statement
The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Disclosure Information

In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Dr. Mobeen Syed Author declares no conflict of interest.

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