NK cells originate from the lymphoid progenitors, however, these cells function as the innate arm component. NK cells induce apoptosis in the infected and cancerous cells. NK cells secret perforins and granzymes for this purpose. NK cells are activated by IL-12 from the macrophages and IFN alpha and beta from the infected cells. NK cells can in turn release IFN gamma to activate the macrophages.
References Natural Killer Cells: Development, Maturation, and Clinical Utilization - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099181/
Stem cell - Wikipedia https://en.wikipedia.org/wiki/Stem_cell
MD., MSc., MSc., BSc
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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fisher6000@*.com
Feb 26 2023, 9:26 pm
Thank You Dr Been for your great lectures. They are above my level of knowledge, but the art work is amazingly helpful.
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Feb 25 2023, 6:48 am
absolutely brilliant teaching - Thank you Dr Been