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NAC N-Acetylcysteine

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2 Comments

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govender@*.com

May 07 2021, 4:09 pm

Brilliant insights simply explained.

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imuzaffar@*.com

Jul 07 2020, 3:14 am

Dr Syed, thank you for a very informative lecture on NAC. I would like to have your comment on some of these warning shots re NAC as well. https://blogs.sciencemag.org/pipeline/archives/2019/10/04/n-acetyl-cysteine-a-warning-shot

WHO's list of essential medicines: safest and most effective drug needed in the health system.

Used for acetaminophen/paracetamol overdose and to loosen thick mucus.
Appears to be safe in pregnancy

How does NAC break disulfide bonds?
https://www.researchgate.net/figure/Structural-formula-of-N-acetylcysteine-NAC-A-Disulfide-bonds-in-proteins-P-can-be_fig1_299401240

It increases the levels of glutathione in paracetamol overdose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/

Role of glutathione in immunity and inflammation in the lung
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048347/

Disulfide bond reduction of vWF
https://www.ncbi.nlm.nih.gov/pubmed/20946172

N-Acetylcysteine as an antioxidant and disulfide breaking agent: the reasons why
https://www.tandfonline.com/doi/full/10.1080/10715762.2018.1468564

NAC functions
https://www.sciencedirect.com/topics/chemistry/cysteine

In this talk, we are going to discuss the following topics:

  1. The functions of N-Acetyl-Cysteine(NAC).
  2. The role of NAC in the fight against SARS-COV-2 in COVID-19 patients.
  3. Why NAC is better than L-Cysteine as a supplement to administer.
  4. The functions of L-Cysteine.
  5. The role of NAC in replenishing glutathione.
  6. The functions of glutathione.

Presented by Dr. Mobeen Syed

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Author declares no conflict of interest.

In addition to the presenter, following authors who may have helped with the content writing, review, or approval declare no conflict of interest.

  • Dr. Mobeen Syed
  • Dr. Pei Purdom (DNP)
  • Dr. Benish Zahra
  • Dr. Iqra Batool
  • Dr. Heba Alzawahri

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