Understanding inflammation is paramount for healthcare students, clinicians/healthcare professionals, and research workers. Most books start the discussion of inflammation by describing the events at the site of injury or infection. This series of medical concepts needs the learner to put the bigger picture together by themselves. We want to take a different approach. We would like to start from the actual final pathways that work to create inflammation. Once we understand these pathways, then the cellular, biochemical, and stress/injury signals can be learned. The intent is that this approach will lead you to have the actual mechanics in your mind while you study the participants of the inflammatory process.
Today we will learn:
What is inflammation?
Why is inflammation needed?
What are the phases of inflammation?
What are the types of inflammation?
The key inflammatory pathways.
Inflammatory Response Pathway | Thermo Fisher Scientific - US
https://www.thermofisher.com/us/en/home/life-science/cell-analysis/signaling-pathways/inflammatory-response-pathway.html
Signaling Pathways in Inflammation and Anti-inflammatory Therapies
https://accessapps.amdi.usm.my/reqba_uploads/article/0002B.pdf
Signaling Pathways in Inflammation and Anti-inflammatory Therapies - PubMed
https://pubmed.ncbi.nlm.nih.gov/29589535/
Signaling Pathways in Inflammation and Anti-inflammatory Therapies | Bentham Science
https://www.eurekaselect.com/article/89351
TLR Pathway
Frontiers | Toll-Like Receptor Signaling Pathways
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2014.00461/full
fimmu-05-00461-g001.jpg (992×952)
https://www.frontiersin.org/files/Articles/112681/fimmu-05-00461-HTML-r1/image_m/fimmu-05-00461-g001.jpg
fimmu-05-00461-g002.jpg (992×858)
https://www.frontiersin.org/files/Articles/112681/fimmu-05-00461-HTML-r1/image_m/fimmu-05-00461-g002.jpg
NLRP Pathway
Frontiers | The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases
https://www.frontiersin.org/articles/10.3389/fnagi.2022.879021/full
Inflammation types:
Chronic Inflammation - PubMed
https://pubmed.ncbi.nlm.nih.gov/29630225/
* Define inflammation and its necessity in tissue response.
* Identify acute, subacute, and chronic phases of inflammation.
* Recognize core initiating and key downstream signaling pathways in inflammation.
* Correlate inflammatory pathways with clinical signs and progression.
MD., MSc., MSc., BSc
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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