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Key Inflammatory Pathways (Inflammation Part 1)

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Understanding inflammation is paramount for healthcare students, clinicians/healthcare professionals, and research workers. Most books start the discussion of inflammation by describing the events at the site of injury or infection. This series of medical concepts needs the learner to put the bigger picture together by themselves. We want to take a different approach. We would like to start from the actual final pathways that work to create inflammation. Once we understand these pathways, then the cellular, biochemical, and stress/injury signals can be learned. The intent is that this approach will lead you to have the actual mechanics in your mind while you study the participants of the inflammatory process.

Today we will learn:
What is inflammation?
Why is inflammation needed?
What are the phases of inflammation?
What are the types of inflammation?
The key inflammatory pathways.


Inflammatory Response Pathway | Thermo Fisher Scientific - US
https://www.thermofisher.com/us/en/home/life-science/cell-analysis/signaling-pathways/inflammatory-response-pathway.html

Signaling Pathways in Inflammation and Anti-inflammatory Therapies
https://accessapps.amdi.usm.my/reqba_uploads/article/0002B.pdf
Signaling Pathways in Inflammation and Anti-inflammatory Therapies - PubMed
https://pubmed.ncbi.nlm.nih.gov/29589535/
Signaling Pathways in Inflammation and Anti-inflammatory Therapies | Bentham Science
https://www.eurekaselect.com/article/89351

TLR Pathway
Frontiers | Toll-Like Receptor Signaling Pathways
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2014.00461/full
fimmu-05-00461-g001.jpg (992×952)
https://www.frontiersin.org/files/Articles/112681/fimmu-05-00461-HTML-r1/image_m/fimmu-05-00461-g001.jpg
fimmu-05-00461-g002.jpg (992×858)
https://www.frontiersin.org/files/Articles/112681/fimmu-05-00461-HTML-r1/image_m/fimmu-05-00461-g002.jpg

NLRP Pathway
Frontiers | The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases
https://www.frontiersin.org/articles/10.3389/fnagi.2022.879021/full

Inflammation types:
Chronic Inflammation - PubMed
https://pubmed.ncbi.nlm.nih.gov/29630225/

* Define inflammation and its necessity in tissue response.

* Identify acute, subacute, and chronic phases of inflammation.

* Recognize core initiating and key downstream signaling pathways in inflammation.

* Correlate inflammatory pathways with clinical signs and progression.

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Faculty

In addition to the presenter, following authors may have helped with the content writing, review, or approval:

  • Dr. Mobeen Syed

CME, CE, CEU and Other Credit Types:

ACCME Accreditation Statement
The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Disclosure Information

In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Dr. Mobeen Syed Author declares no conflict of interest.

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Instructors

Dr. Mobeen Syed

Dr. Mobeen Syed

MD., MSc., MSc., BSc

Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.

Inflammation

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