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JAK-STAT Pathway - (Inflammation Part 6)

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Sep 06 2024, 7:51 pm

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Imagine a complex communication network inside your cells. This network, called the JAK/STAT pathway, is like a cellular messenger system. It carries signals from molecules outside the cell, like hormones or immune messengers, all the way to the control center of the cell, the nucleus. This pathway plays a vital role in many functions, including inflammation. When this system malfunctions, it can contribute to chronic inflammatory diseases. In this lecture, we'll explore how the JAK/STAT pathway works and how it's linked to conditions like rheumatoid arthritis and psoriasis.

Disclaimer:

This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

 

DrBeen: Online Personalized Medical Education - DrBeen
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* Understand the components and basic functions of the JAK-STAT signaling pathway.
* Describe the mechanism of JAK-STAT signaling, including receptor activation and transcriptional activity.
* Identify clinical conditions associated with JAK-STAT dysregulation.
* Explain the regulation of the JAK-STAT pathway by proteins like SOCS, PiAS, and PTPS.
* Discuss therapeutic modulation of the JAK-STAT pathway.
* Recognize drugs that inhibit the JAK-STAT pathway.

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Faculty

In addition to the presenter, following authors may have helped with the content writing, review, or approval:

  • Dr. Mobeen Syed

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The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


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In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Dr. Mobeen Syed Author declares no conflict of interest.

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Instructors

Dr. Mobeen Syed

Dr. Mobeen Syed

MD., MSc., MSc., BSc

Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.

Inflammation

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