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JAK-STAT Pathway - (Inflammation Part 6)

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Sep 06 2024, 7:51 pm

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Imagine a complex communication network inside your cells. This network, called the JAK/STAT pathway, is like a cellular messenger system. It carries signals from molecules outside the cell, like hormones or immune messengers, all the way to the control center of the cell, the nucleus. This pathway plays a vital role in many functions, including inflammation. When this system malfunctions, it can contribute to chronic inflammatory diseases. In this lecture, we'll explore how the JAK/STAT pathway works and how it's linked to conditions like rheumatoid arthritis and psoriasis.

Disclaimer:

This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

 

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* Understand the components and basic functions of the JAK-STAT signaling pathway.
* Describe the mechanism of JAK-STAT signaling, including receptor activation and transcriptional activity.
* Identify clinical conditions associated with JAK-STAT dysregulation.
* Explain the regulation of the JAK-STAT pathway by proteins like SOCS, PiAS, and PTPS.
* Discuss therapeutic modulation of the JAK-STAT pathway.
* Recognize drugs that inhibit the JAK-STAT pathway.

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

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The DrBeen Corp designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


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Faculty Disclosures
Author declares no conflict of interest.

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