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Hypersensitivity Pneumonitis

Duration: 16:35

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This video is part of the series of videos discussing restrictive lung diseases. 
We will discuss hypersensitivity pneumonitis in this talk.

  • Definition
    • Alveolitis due to inhaled external allergens. 
    • Involves smaller airways and the respiratory zones instead of the large airways.
  • The difference of this disease from asthma.
    • This is a mixture of type III and type IV allergies.
  • Pathophysiology of the hypersensitivity pneumonitis
    • Macrophages
    • Allergen presentation to T and B cells in the lymph nodes.
    • Interleukins released.
  • Phases
    • Acute and Chronic.
    • Role of neutrophils and T cells in the acute phase.
    • Granuloma formation in the chronic phase.
    • Why hypersensitivity pneumonitis is also classified as a granulomatous disease.
    • IL4, IL5, IL12, C5a
  • Scarring of the respiratory zones.
  • Clinical Presentation
    • Fever, dyspnea, cough, lethargy, malaise, restrictive lung disease.
    • FEV1 reduced
    • FEV1/FVC increased due to increased elasticity and rapid expulsion.
    • Monday morning blues experienced by the patients.
  • Industries/tasks that can cause this disease
    • Fungi and bacteria from farming work - farmers lungs. 
    • Micropolyspora fanny and bagassosis. 
    • Thermophilic actinomycetes.Cheese workers - moldy cheese. 
    • Penicillium casey.
    • Miller's lungs. 
    • Dusty grain.Animal products, pigeon breeder's lungs. 
    • Pigeon droppings have pigeon serum proteins.
    • Other chemical industry workers.

In this video we will learn about :

1. Definition of hypersensitivity pneumonitis. 

2. Pneumonitis vs. Asthma. 

3. Pathogenesis of acute and chronic reaction. 

4. Type III and IV hypersensitivity reaction. 

5. Effect on capacities and volumes. 

6. Clinical signs and symptoms 

7. Predisposed population. 

 

 

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Faculty

In addition to the presenter, following authors may have helped with the content writing, review, or approval:

  • Dr. Mobeen Syed

CME, CE, CEU and Other Credit Types:

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The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Disclosure Information

In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Dr. Mobeen Syed Author declares no conflict of interest.

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Instructors

Dr. Mobeen Syed

Dr. Mobeen Syed

MD., MSc., MSc., BSc

Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.

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