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Functions and Effects of Angiotensin II: A Mechanistic Review

Duration: 1:15:03

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anusuya@*.com

Jul 16 2025, 1:16 pm

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In this lecture, we will explore the physiological and pathological effects of Angiotensin II, a key effector of the renin-angiotensin-aldosterone system (RAAS). Based on Goodman & Gilman, we will examine three major domains of Angiotensin II action:
Altered Peripheral Resistance – including vasoconstriction and enhanced sympathetic activity 
Altered Renal Function – focusing on sodium reabsorption, aldosterone release, and renal hemodynamics
Altered Cardiovascular Structure – covering hypertrophy and remodeling effects

Objectives:

  • Understand the mechanisms by which Angiotensin II influences vascular tone, renal function, and cardiac structure
  • Identify the acute and chronic outcomes of Angiotensin II signaling
  • In the next lecture, we will link these effects to therapeutic targets of ACE inhibitors and ARBs

Functions and Effects of Angiotensin II

Brunton, Laurence; Knollman, Bjorn; Hilal-Dandan, Randa. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition (Goodman and Gilman"S the Pharmacological Basis of Therapeutics) (p. 1825). McGraw Hill LLC. Kindle Edition.

 

  • Understand the mechanisms by which Angiotensin II influences vascular tone, renal function, and cardiac structure
  • Identify the acute and chronic outcomes of Angiotensin II signaling
  • In the next lecture, we will link these effects to therapeutic targets of ACE inhibitors and ARBs

Following answers are created by ChatGPT. Occasionally the answer may be harmful, incorrect, false, misleading, incomplete, or limited in knowledge of world. Please contact your doctor for all healthcare decisions. Also, double check the answer provided by the AI below.

Faculty

In addition to the presenter, following authors may have helped with the content writing, review, or approval:

CME, CE, CEU and Other Credit Types:

ACCME Accreditation Statement
The DrBeen Corp is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA Credit Designation Statement
The DrBeen Corp designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Disclosure Information

In accordance with the disclosure policies of DrBeen Corp and the ACCME (Accreditation Council for Continuing Medical Education), we are committed to upholding principles of balance, independence, objectivity, and scientific rigor in all of our Continuing Medical Education (CME) and Continuing Education (CE) activities. These policies include the careful management and mitigation of any relevant financial relationships with organizations that are not eligible.
All members of the Activity Planning Committee and presenters have disclosed their relevant financial relationships. The DrBeen Corp CE Committee has thoroughly reviewed these disclosures and determined that these relationships are not deemed inappropriate in the context of their respective presentations. Additionally, they are found to be consistent with the educational objectives and the integrity of the activity.

Faculty Disclosures
Author declares no conflict of interest.

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