In this lecture, we will explore the physiological and pathological effects of Angiotensin II, a key effector of the renin-angiotensin-aldosterone system (RAAS). Based on Goodman & Gilman, we will examine three major domains of Angiotensin II action:
Altered Peripheral Resistance – including vasoconstriction and enhanced sympathetic activity 
Altered Renal Function – focusing on sodium reabsorption, aldosterone release, and renal hemodynamics
Altered Cardiovascular Structure – covering hypertrophy and remodeling effects

Objectives:

• Understand the mechanisms by which Angiotensin II influences vascular tone, renal function, and cardiac structure
• Identify the acute and chronic outcomes of Angiotensin II signaling
• In the next lecture, we will link these effects to therapeutic targets of ACE inhibitors and ARBs

Functions and Effects of Angiotensin II

Brunton, Laurence; Knollman, Bjorn; Hilal-Dandan, Randa. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition (Goodman and Gilman"S the Pharmacological Basis of Therapeutics) (p. 1825). McGraw Hill LLC. Kindle Edition.