Famotidine (H2 Receptor Antagonist)
Famotidine (H2 Receptor Antagonist)
MATH+ '+' protocol advocates the use of Famotidine based on the study showing reduction in the risk of intubation and death in COVID-19 patients.
Famotidine, sold under the brand name Pepcid among others, is a medication that decreases stomach acid production.[2] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.[2] It is taken by mouth or by injection into a vein.[2] It begins working within an hour.[2]
Common side effects include headache, intestinal upset, and dizziness.[2] Serious side effects may include pneumonia and seizures.[2][3] Use in pregnancy appears safe but has not been well studied while use during breastfeeding is not recommended.[4] It is a histamine H2 receptor antagonist.[2]
Famotidine
https://en.wikipedia.org/wiki/Famotidine
Gastrin
https://en.wikipedia.org/wiki/Gastrin
Enterochromoaffin-like cells
https://en.wikipedia.org/wiki/Enterochromaffin-like_cell
In this lecture Dr. Mobeen will discuss:
1. The use of famotidine in MATH+ protocol. (00.40)
2. Different types of H2 blockers. (1:49)
3. Physiology of gastric acid secretion. (3:55)
4. Role of prostaglandin in gastric acid secretion and the adverse effect of non-steroidal anti-inflammatory drugs. (11:05)
5. Function of the vagus nerve in gastric acid secretion. (14:30)
6. Mechanism of action of famotidine. (15:12)
7. Pharmacokinetics and pharmacodynamics of famotidine. (18:37)
8. Uses and side effects of famotidine. (20:33)
9. Preprint observational study findings with the use of famotidine in COVID-19 patients. (21:00)
Presented by Dr. Mobeen Syed
MD., MSc., MSc., BSc
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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