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Endothelial injury prior to covid infection
Sondang Aemilia - 2021-03-30 17:18:41

Dr Mobeen, what do you think about TMAO (Trimethylamine N oxide) and AGEs (Advanced glycation End Products) that is causing endothelial injury. This is also the main cause of plaque, coronary heart disease and stroke. Can this contribute to blood clotting in certain patients ? Maybe these patients were never evaluated for their TMAO level in the blood or urine, sudenly got covid and become severe with thrombosis ? Is that possible ? At least this is my theory.

Endothelial injury prior to covid infection
Sondang Aemilia - 2021-03-30 17:23:43

Here is one article about TMAO: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462523/


Here is another about AGEs / sRAGE: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983090/

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Matthew Isaacs - 2021-04-11 00:27:45

You bring up a great point.  With all of the clear data on comorbidities, it's clear that baseline health is super important!

If there was ever a time people should focus on their health, it's now.  Yet so many have put on the "quarantine 15".  Not good.

COVID is a warning to everyone to do our best to be healthy.  We shouldn't be looking for a magic drug (including vaccine) to make us healthy.

Most of us have at least a basic idea of what foods are best for health -- we just aren't doing it.  (There's virtually no one saying that fresh organic vegetables are the problem, LOL!)

Nutritional science needs much more research support.  It doesn't not have the financial backing from government, academia, or the private sector that it deserves.

A major organization that focuses on nutrition research is badly needed.  

Grassroots Health is trying to implement wide-scale nutrition and health marker testing (by offering reasonably priced at-home test kits) and data gathering, which is great!  But much more needs to be done.