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Microbiology - (UW - 4354) HIV vs Mono
Mobeen Syed, MD - 2018-09-23 18:01:21

Primary HIV infection causes a febrile illness that can closely resemble infectious mononucleosis. Most frequently, patients with acute HIV have fever, malaise, generalized lymphadenopathy, sore throat, headache, rash, and Gl symptoms The key distinctions between the two are that rash (unless antibiotics have been administered) and diarrhea are LESS common in infectious mononucleosis and tonsillar exudates are uncommon in primary HIV. It would be reasonable to check an HIV antibody test or plasma HIV RNA if his heterophile antibody test is negative

Microbiology - (UW - 4354) HIV vs Mono
Mobeen Syed, MD - 2018-09-23 18:01:48

Classically, infectious mononucleosis is characterized by mild to moderate fever, pharyngitis, and lymphadenopathy The lymphadenopathy tends to be symmetric and affects the posterior more than the anterior cervical lymph nodes. Generalized lymphadenopathy may also occur. Splenomegaly with splenic rupture is a rare complication

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