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Microbiology - Escherichia Coli (4169)
Mobeen Syed, MD - 2018-09-18 16:36:47
Treatment of Pyelonephritis
Uncomplicated:
- Mild to moderate: Trimethoprim-sulfamethoxazole, fluoroquinolones (ciprofloxacin) (all usually oral)
- Severe: Ceftriaxone, fluoroquinolones (ciprofloxacin, levofloxacin), trimethoprim-sulfamethoxazole (all usually intravenous)
Complicated
Indwelling urinary catheter, urinary obstruction or
retention, recent urologic procedure or hospital-acquired
infection, underlying renal impairment with azotemia, immunosuppression & comorbid diabetes. All are usually treated with hospitalization & intravenous antibiotics.
- Mild to moderate: Ceftriaxone, cefepime, fluoroquinolones (ciprofloxacin, levofloxacin)
- Severe: Ampicillin-sulbactam, ticarcillin-clavulanate, piperacillin-tazobactam, meropenem, imipenem, aztreonam (+/-gentamicin)
Pregnancy
Usually hospitalized for intravenous antibiotics
- Ceftriaxone +/- gentamicin, aztreonam
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Microbiology - Escherichia Coli (4169)
Mobeen Syed, MD - 2018-09-18 16:49:39
UW 4257. E Coli can also cause osteomyelitis in immunocompromised patients (diabetics for example.) Escherichia coli and Klebsiella pneumoniae may cause osteomyelitis (especially in patients with diabetes mellitus), but both microorganisms are far less common than Pseudomonas in patients with puncture wounds. |