In this fascinating in-vitro and ex-vivo study the researchers from Harvard Boston and Cairo found the mechanism of impaired immune system during the cold temperatures. Researchers found that the extracellular vesicles produced as a result of toll-like receptor 3 (TLR3) are functionally impaired and reduced in numbers when the temperature drops in the anterior nasal mucosa even by 9 degrees Fahrenheit. Let's review this fascinating study.
Cold exposure impairs extracellular vesicle swarm–mediated nasal antiviral immunity - Journal of Allergy and Clinical Immunology https://www.jacionline.org/article/S0091-6749(22)01423-3/fulltext#%20
Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity https://www.jacionline.org/action/showPdf?pii=S0091-6749%2822%2901423-3
MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19 - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910799/#:~:text=In%20fact%2C%20miRNAs%20have%20been,or%20by%20enhancing%20the%20expression
Why colds and flu viruses are more common in winter | CNN https://www.cnn.com/2022/12/06/health/why-winter-colds-flu-wellness/index.html
MD., MSc., MSc., BSc
Mobeen Syed is the CEO of DrBeen Corp, a modern online medical education marketplace. Mobeen is a medical doctor and a software engineer. He graduated from the prestigious King Edward Medical University Lahore. He has been teaching medicine since 1994. Mobeen is also a software engineer and engineering leader. In this role, Mobeen has run teams consisting of hundreds of engineers and millions of dollars of budgets. Mobeen loves music, teaching, and doing business. He lives in Cupertino CA.
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2 Comments
empower@*.com
May 12 2023, 2:55 am
Wonderful new video. Great illustrations too 😎. I knew my poor nose needed to stay warm!
anne.fulbright@*.com
Apr 03 2023, 12:26 pm
My nose gets warmer when I sip tea in the morning. Although my habit of opening bedroom windows during cool nights may have to be curtailed. Cool study, thank you!